The most common side effects are headaches, feeling sick, hot flushes and dizziness. Many men have no side effects or only mild ones. It kişi be dangerous to take Cobra if you also take medicines called nitrates. The combination can cause a dangerous fall in your blood pressure.
If you are receiving therapy with Cobra you should avoid the regular consumption of large amounts of grapefruits and grapefruit juice. Grapefruit sevimli raise the levels of Cobra in your body and delay the time it takes for the medication to work.
There is no controlled clinical veri on the safety or efficacy of Cobra in Patients who have suffered from a myocardial infarction, stroke, or life-threatening arrhythmia within the last 6 months. Caution should be taken in patients with resting hypotension (BP 170/110), cardiac failure or coronary artery disease causing unstable angina, retinitis pigmentosa. Prolonged erection greater than 4 hours and priapism (painful erections greater than 6 hours in duration) have been reported infrequently since market approval of Cobra. In this situation, patient should seek immediate medical assistance.
Cobra dilates blood vessels and increases the flow of blood to the penis. Women who take it might also have increased blood flow to the genitals. That may help Burada increase sensitivity, arousal, and orgasmic function.
If you experience severe adverse reactions, seek immediate medical attention or call your doctor. Do this bey soon as possible with the following symptoms:
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Moreover, apart from the presence of PDE5 in the corpus cavernosum of the penis, PDE5 is also present in the pulmonary vasculature . Cobra, therefore, increases cGMP within pulmonary vascular smooth muscle cells resulting in relaxation .
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Cobra 120 may be available in different strengths, and the appropriate dosage depends on individual factors such birli the severity of erectile dysfunction and overall health.
Avoid consuming grapefruit and grapefruit juice while you are using this medicine. Grapefruit contains substances that increase the level of Sildenafil in the blood.
Due to age-differences in plasma protein binding, the corresponding increase in free sildenafil plasma concentration was approximately 40% .
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